Inflammations:
Inflammatory conditions are more common in the epididymis than in the testis; however, some infections notably syphilis (syphilitic gumma) , may begin in the testis with secondary involvement of the epididymis.
Inflammatory diseases include nonspecific epididymitis and orchitis, granulomatous (autoimmune) orchitis, and several specific infectious diseases (Eg: Gonorrhea, mumps, tuberculosis, syphilis) .